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急性髓系白血病治疗进展新药与新挑战
文章来源：急性白血病 发布时间:2020-12-15 3:04:30 点击数： 次
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AdvancesintheTreatmentofAcuteMyeloidLeukemia:NewDrugsandNewChallenges
Date:类型：Review
Author:NicholasJShortetal.
杂志:CancerDiscov
摘要
Thetherapeuticarmamentariumofacutemyeloidleukemia(AML)hasrapidlyexpandedinthepastfewyears,drivenlargelybytranslationalresearchintoitsgenomiclandscapeandanimprovedunderstandingofmechanismsofresistancetoconventionaltherapies.However,primaryandsecondarydrugresistanceremainsasubstantialproblemformostpatients.ResearchintothemechanismsofresistancetothesenewagentsisinformingthedevelopmentofthenextclassofAMLdrugsandthedesignof
